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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f2f70bdf94335b6208be34a4e5087b8f719e54d05937087d7349e896d41bd8' 
  AND token = 'HoqRkBIusuqo/cTObCGTtN+6RSoyNdR/E4IvsqqDNNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}