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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59994a0f48baf11a43bfd950aec051f6d7be941b22253fa821e2622f45fe2f41' 
  AND token = 'oRBEyAYylAZylgTQH5+lbVg3h6e5DKwy+/tlYhnmJgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}