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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2149d4d2c46632a47d2531094eecb3705bacb360453aa63588951cc31dfde7f6' 
  AND token = 'XPZk4QuWVB6znTbm7pNwUmyr1HHiG+l+gEPCtkTEN60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}