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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f68626c9c45347bc7cdc0cb6f5482421abf165784c905f88b43e54bc9e82690' 
  AND token = 's9w0avjBOLB2NfZ/Tc3SX0KhOJpejGo/0bTZRf6M1JQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}