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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e99a86b3f39e7f9bfb19db177705a1de8047f0010924b02e4504fe62f00be2fc' 
  AND token = 'CxDlmJs9Np7VXg2WFDitrtamZuSq+7t4/S97qU58h/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}