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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5403884928ebbeb96d6b203a9d97927774e47abdceea32fdada0c4fd29947c40' 
  AND token = 'wDIDJj9A5q+AJydZFbkMAlsiXfBqeeHeqaqJUl2wZ4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}