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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9c90015a4356ff5e272c58b6f0e6b1e0c0a7373e4836a74169cc739de1baf0' 
  AND token = '6JIa1zWxiZ/a23aEA/WM2t99WtRfiK5Ndv/BPGvuj6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}