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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18dc3ce56ea5d5a65d5442993394b99e7b60b08780aa53cefbad3ee617c6d4a' 
  AND token = 'Z+wq1apx1FB61e5RUHLEFoo8LA5wGp9S/bz/qsrNsH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}