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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dfb33c40f399ac05b6b719e72380f2a6801ebf0bece8f8d66b0606e5670b75d' 
  AND token = 'k+3NVfmcVQUKhR5/ievtqFjLNkxEEB8HlEnMx6R4/FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}