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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef4c9d314eaf4341b80ddb8ad5c8e0b2c6ee408484f5e5e6710ffaea2527691' 
  AND token = 'arFO/eX7XsC/LhzxV6wJ/hejaGYBVCi2Cd6m0WtsJKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}