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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105101e81fb86334c78b7b02325ca6358a0bc37b61e514fb89b859d86e357a26' 
  AND token = 'vmBXfJg1IX7Ivnc15J1uCOTmSu2wHtktDMtEBXEoO98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}