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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a32fffe6a4fa526d5ae8970cc3b86686c88bc2633d13a840548ff01fa9edb03' 
  AND token = 'cmtztKS4XkWIvx/wS3AMX0xUzNZD0Tl9Qpg0BiYV9BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}