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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd207b6c5e4755c0253b227b97b91ef94043c730c365dbedf1d17e3a1662dc09' 
  AND token = 'YXADpZl3UeivyaD/hyXIfjfp7inNvL1JJ78ILJWB/UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}