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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd6108beb540450e7a89d1bfb73025de1e4854dde6b8500c35260a86c05dcc2c' 
  AND token = 'rVOigpIuynKECxn/1mb7BTHFzogjHXM+rz28JIWQqsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}