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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a63b6c3a9f73b2d9a5afe0f15d69a4093e13911c4217432c63b1d2f626a1f48' 
  AND token = 'A6jxnUofsU8aGRjYdgDdaTuJXjIqoWBqO6cc2vJ+eyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}