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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc96fce20884ecec05500d58d9cb88899d2ff8db76cf04a4913f18447d499b9' 
  AND token = 'dP7rP+xpUdKI4zXmAwXeuWC+mKsG/irF0EkJcjHrP+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}