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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40b037bea9a1885b2f1dbecc3c2330bd7e210ee8a015949834ca7e8081b9654a' 
  AND token = '+LI7cnWcTkLrMm6zzMhVvzg7TGE5BIkprDOEjAVc+Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}