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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd2a91ecd38201d11d0a10ab6118f318ddde5f13562e9c3f25f2085ba4fa3b49' 
  AND token = 'bxU0xI/XwV2EIMRe6XVDb+7sRGzu8mhhMJrlbwqtLoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}