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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4f549cf30e8b555d12e59c78bd9e6c34ad24c19d14f019054d0fb97e62d09f' 
  AND token = '0+r09R7pgyBPQgUn48rAEfFDbHlZpwUxlpz8tzU3noY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}