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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1ac01212d532bd5744e665f1f9d6ff484d6bbb8dc34a37da80bb797e0935c5c' 
  AND token = 'vc9tppx6D7z04CLc4Kan/521xLOzf23n5Zq45f44Usc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}