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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed90b8f8c88f658ab8bca2d657b03e9b2860878177cf5a12bd8030d4a999ebf' 
  AND token = 'O/juYjncHJjdu9UnTRBcTA5hidcO3X6gXuhMBEKfM/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}