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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '214ed8d7858e8622b919e316ef25aad7b72c586205dca2af6a2f92a05d1e0d8a' 
  AND token = 'BGEfvm6zUZNYRPGa00P4b4Fu3lvEtfKOdhOL9+Sz5sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}