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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d6959ef9b1c1f7e92ea27776cb7a0516a1145eb7fa8a993953ae02e652bdcf' 
  AND token = 'nQr1t0yUCSpiHyr+HqbYBN1ZXyCVUhRIDj7Vm3Gp3/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}