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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f0a6cb3c9d1083c60d4f51ee86a2f338f9b03030354a976b88abcf4206556d8' 
  AND token = 'KCIAMUsrVqayLy+mTMm1p8Wy4tbE5thTr7vIX4m6kbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}