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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b5b256d4cf3af88bb0c5ef910f95b33bcdf0502d13afa272303480e03629f7' 
  AND token = '6GZzbsRng/jwD0Yv8xAlMDo5StMbIGlBsYiQud287Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}