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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4532914a20db30c8103e8edd3246b84c45e4c1cf33d565c924ba7952590e36fd' 
  AND token = '3r7s0m/1+FTiVB4cvCM3QVNVIuTeWMF3kTov11rz+EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}