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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e06aa9d4307f6a1c293442df5a42e567b5a56cee2bd8a7d855f904e22bd194' 
  AND token = 'S1G7DtspjZ3SwXGw1gxaC/tQtNnc0bm7AmeArDV1qd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}