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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5996664eef89d622b872585907b257732a9e1b88b81cde5c3f5d36ecae15dc5a' 
  AND token = '+5GTtoAvaHr6tBEEOLqFcfYuEXqHjIUSVsCWPSjdD/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}