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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44010c3c110d2c7b53fa90179e8d115c90d1c0e065506f1b8f195f1baab023a6' 
  AND token = 'n8F7bB2dISiY+ml1+x52h6Kc9dTGdJ/4B9uNbKpNeyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}