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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e82b58a7d7fd4875b1d56d6020944a54e0cf3230a4ffac51a6171e1fa0e0542' 
  AND token = '8GUlDiPiY1XVSdsqhu6rUJmps055kgHIkCbhydTHJSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}