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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d50614fe325f8340b2897f1ed588f760a1550a71254ead26fc79d797fe9947' 
  AND token = 'd8U09zWQOZdcflNu5l8rNxvBUUklpi4nMtp9eDzcISM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}