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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20a305323c17d61f4d5effc6fa3c6021a787740f26d2f6352840ba93f34b9bd1' 
  AND token = 'kU1uK5XoDiv0v1gsQZPuOmQRn+cptsfZpLHCyeXm9e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}