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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123518d71bb31b3e4ee39b9a0a0a2955c413e89c0e57a97480aa4d7f56772aa5' 
  AND token = 'yyPSEMIc4Q3wuF6c86FK/Mjrhf3r/Mc/iRBb4QAh1vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}