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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5c3a5820770e561d0d1b004ab799815025e53fe2c62ba7ad8020e70e86b7c0' 
  AND token = 'IPgcdgQqv2JFuLgPKmCj6JjSwZBxtd2VPodnq9syCFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}