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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b7bd31d6dd926725dfb22d3f1f4c8afdb290639eca90f3c7cd0518e30c6854' 
  AND token = 'sArytpaC/dO1yVQ5yh3sC1Lfh0PFnLZ6sHnZgtbHL54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}