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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ceb04e3ca70de5edca4cf901d6152d36ad642b2fcf318a42281d3f10dd9c8f1' 
  AND token = 'qnvLXLXrSsr7sZyYc6tby9zEiRIRFA04yU8J1eM1nZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}