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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8877e3e56e56fb97bdfa8283200154abac304ad6ff99e8687605e488640353' 
  AND token = '1CERGTb3VSWMtlQ4QU23BBCprW+GrbYijgh0SmKapyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}