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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd54fa7a4745e335ac600798bdb23b003da645b55792c25693ff1e419d965203' 
  AND token = '12AKQ8SyJdnz4nl+vSAnvjq0XXeS8SJ2VixyfL4hwUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}