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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c99d8c58576201f55f02dedb81bb2f0af2ba225156c13e5d2ccea21e0e28338' 
  AND token = 'sHVwSs09z76dfIU3M28xtcX4euYRFwaxtEFjNND2wS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}