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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c163b690ff3c464a13fb2e386b222b7adf6a6a4170545c23774d2f18f8271473' 
  AND token = 'iEHQfNbV2Xym7ebN8zCUqzKriOGwif9ZluioKb1H5O4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}