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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ada0147a8e448a6c99dffce3a3b7400031a3283769535c16f3d06f52ee10f5' 
  AND token = 'ozc5KYJzuy96vCLLz08B9Y+Mu4sAHwRSkeTHVNRZT4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}