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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538d9c0cbd7c433d89c5a8c9ad377a876807d2dff20378449a230daf0bc640ac' 
  AND token = 'qHvMAz9wuuZfL2ViaL5CTqcMdCDA3JwZnpXP+HqEaNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}