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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7cc900d705319820bd0b73acd31197e3b03c41c281d0696f96bcd942723373f' 
  AND token = 'twn3tPKb/x7gWBsDVz5njSrvrgUfP3HBFBI0l27OSc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}