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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d176e0706fa179dfb69a157dbf78a8e170f7fcf89ef4f112b842c4c4e5f47f0' 
  AND token = 'ZY0FMRJU5upbNo0enlR0Udg7tXtItwBY6WuPUl5cJEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}