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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122c53993ce8393b516e2aeb187883ba7b90ed70e30e6dfe197a7ee645ca403c' 
  AND token = '4gXHKz90HDt1MYnV70dHFzBaezJqV0jQ41ciaUo9ExY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}