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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05eb00e43a67e3245bde97bb1ca2924515b52a254a14276131792601c882e2da' 
  AND token = '400SaqvQbnpnWRtsmryD4b1RheOr4vDvY3P/zGm4o3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}