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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492db1f8fbd362463f730f09461a1181c5430cedb4e06391b4516002b0376035' 
  AND token = 'wX/IcjlqbqNKwx8Yr8GBKtFkUGmgYI5gWcRr0CNB66Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}