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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea668700b76eaa2ad02882e80cd8ef2d0921494e0a628e17245a4ff187dc8a8' 
  AND token = 'mnPvCUHtVW6jIzQ2B+2Mc8jcZ/0zT9ZAhgNagorto8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}