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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '886aa6b4a990668a176f75adb3fae3ef33ae933f34de7b9b00c34e547fb4a1da' 
  AND token = 'ANKYLRZs6YSlB3aht4kL0yBW320TIZWu8Bg0jJDWsNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}