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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6e1fc2a15bff22eb719f0be296358386657d2c2fd6baad8b70d187c89c52c9f' 
  AND token = 'lHaZA7GCMHD1GEaNaAx6AtsuoU+MzxtGY9FtjzAiCD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}